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Atrial fibrillation

Prevalence
Causes
Clinical features
Investigations
Therapy
Prevention
Prognosis
Prognosis

Half of patients with acute AF revert spontaneously to sinus rhythm within 18 hours. b

Recurrence

Recurrent symptomatic attacks are common in patients with paroxysmal AF b
Few patients with chronic AF remain in sinus rhythm long-term following cardioversion. a  
Patients are more likely to revert to AF if they

  • had AF for more than 3 months a  
  • have severe heart failure a  
  • are old a  
and less likely if they have non-rheumatic mitral valve disease  a  

Anti-arrhythmic side-effects are common a  

Stroke

Atrial fibrillation is an important risk factor for stroke. a  
The risk of stroke is increased further with

  • a history of hypertension a  
  • previous TIA or stroke a  
  • ischaemic heart disease a b  
  • diabetes mellitus a  
  • recent heart failure a  
  • increasing age a  
and possibly
  • markers of LV dysfunction a  
  • cardiomegaly  b  
Use the following clinical prediction rule to determine your patient's risk of having a stroke.

Clinical prediction rule to rank your patient's risk of a stroke

CHAD-2 stroke risk factors Score
Congestive hear failure +1
Hypertension +1
Aged 75 or older +1
Diabetes mellitus +1
History of stroke or transient ischaemic attack +2

Risk of a stroke 

Score Risk of a stroke
0 to 2 low
3 to 5 medium
6 high

Patients with atrial fibrillation who have a stroke are at increased risk of having a severe stroke or dying a  

Peripheral thromboembolism

Atrial fibrillation increases the risk of peripheral thromboembolism. b  
The risk is increased with

  • younger age at onset of AF b 
  • peripheral atheroscelosis b 

Expiry date: February 2003
Levels of Evidence used in grading these guides

Authors   CM   Ball , N   Shenker
Reviewer   R G   Hart
CAT Writers   CM   Ball , N   Shenker , CJ   Wotton