Therapy

Perform endoscopic haemostasis ^a using epinephrine ^a

Why?

• It reduces the need for emergency surgery, though there is no clear effect on bleeding ^a

Injecting epinephrine into actively bleeding peptic ulcers reduces the need for surgery

Patient	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
upper GI bleed due to actively bleeding peptic ulcer a	epinephrine injection	no injection	emergency surgery	42%	64% (12% to 86%)	4 (2 to 16)