Therapy

Give antacids ^a

Why?

• Antacids help relieve symptoms and improve ulcer healing. ^a
• Acid suppression reduces rebleeding and the need for surgery. ^a

Antacids helps ulcer healing and discomfort

Patient a	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
active peptic ulcers, no H2 or proton pump antagonists	calcium carbonate	placebo	relief of discomfort at 4 weeks	71%	29% (1% to 65%)	5 (3 to 50)
			healing ulcer at 4 weeks	68%	35% (4% to 76%)	4 (2 to 21)