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Upper gastrointestinal bleed

Prevalence
Causes
Clinical features
Investigations
Therapy
Prevention
Prognosis
Prognosis

Death and further rebleeding are common, particularly for
  • inpatients a  
  • patients with varices a  
Rank your patient for risk of rebleeding or dying  a  

The Rockall score can help rank your patient for risk of rebleeding and mortality

a score 0 score 1 score 2 score 3
age aged < 60 aged 60 to 79 aged > 80
shock pulse < 100; systolic bp > 100 mmHg pulse > 100; systolic bp > 100 mmHg pulse >100; systolic bp < 100 mmHg
co-morbidity no major co-morbidity cardiac failure; ischaemic heart disease; any other co-morbidity renal failure; liver failure; disseminated malignancy
endoscopic stigmata none; dark spot seen blood in upper GI tract; adherent clot; visible or spurting vessel
diagnosis Mallory-Weiss tear; no lesion seen and no stigmata of recent haemorrhage all other diagnoses malignancy of upper GI tract

 

pre-endoscopy score a death %
(95% CI)
7 75% 
(45% to 100%)
6 62% 
(50% to 73%)
5 35% 
(27% to 43%)
4 21% 
(17% to 25%)
3 12% 
(8.6% to 16%)
2 5.6% 
(2.8% to 8.5%)
1 3.0% 
(0.63% to 5.3%)
0 0.0% 
(0.0% to 1.2%)

 

post-endoscopy score a death %
(95% CI)
rebleeding
(95% CI)
8+ 40% 
(30% to 51%)
37% 
(27% to 47%)
7 23% 
(15% to 31%)
37% 
(28% to 46%)
6 12% 
(6.3% to 17%)
27% 
(20% to 34%)
5 11% 
(6.3% to 15%)
25% 
(19% to 31%)
4 8.0% 
(4.0% to 12%)
15% 
(10% to 21%)
3 1.9% 
(0.0% to 3.9%)
12% 
(6.8% to 17%)
0 to 2 0.0% 
(0.0% to 0.93%)
5.9% 
(3.3% to 8.5%)

 

Ulcers

Peptic ulcers heal slowly and relapses are common c  

Ulcers are less likely to heal 

  • with increasing age b
  • with cigarette smoking b
  • in men b
  • with persisting ulcer symptoms b
  • with a duodenal ulcer diameter larger than 20 mm b
Relapse is more likely with c
  • duodenal ulcer
  • psychological stress
  • endoscopic findings of scars at ulcer sites on healing
  • no acute therapy

 

Varices

The risk of dying from varices is increased with a

  • worsening Pugh score
  • alcoholism
  • increasing age
  • hepatocellular carcinoma

Expiry date: July 2003
Levels of Evidence used in grading these guides

Author   A   Townsend , CM   Ball
Reviewer   L   Friedman
CAT Writers   A   Townsend , CM   Ball , CJ   Wotton