Prevention

If patients need to continue NSAIDs, consider H. pylori eradication therapy for infected patients without ulcers ^a

Why?

• Eradication therapy reduces development on peptic ulcers ^a

Eradication therapy reduces peptic ulcers in patients starting long-term NSAIDs

Patient	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
H.pylori infection starting NSAIDs a	H. pylori eradication therapy	placebo	peptic ulcer on endoscopy at 8 weeks	26%	74% (14% to 92%)	5 (3 to 23)