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Upper gastrointestinal bleed

Prevalence
Causes
Clinical features
Investigations
Therapy
Prevention
Prognosis
Prevention

H. pylori eradication therapy

Consider adding cetraxate for smokers a

Why?

  • Smokers who receive cetraxate, a mucosal protective agent, have higher eradication rates. a

Adding cetraxate to triple therapy improves eradication rates in smokers

Patient Treatment Comparison Outcome CER RRR
(95% CI)
NNT
(95% CI)
smoker with dyspepsia and H. pylori infection a triple therapy and cetraxate triple therapy H.pylori eradiction
at 4 weeks
55% 69%
(31% to 120%)
3
(2 to 4)
 

Expiry date: July 2003
Levels of Evidence used in grading these guides

Author   A   Townsend , CM   Ball
Reviewer   L   Friedman
CAT Writers   A   Townsend , CM   Ball , CJ   Wotton