Prevention

Consider adding probiotics e.g. Lactobacillus GG ^a

• Lactobacillus GG reduces gastrointestinal adverse effects from H. pylori eradication therapy. ^a
• Adding Lactobacillus acidophilus to triple therapy increases eradication rates. ^a

Lactobacillus GG reduces GI adverse effects from H. pylori eradication therapy

Patient	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
asymptomatic with H. pylori infection on eradication therapy a	Lactobacillus GG	placebo	gastrointestinal adverse effects at 2 weeks	67%	40% (0% to 64%)	4 (2 to 43)

Adding Lactobacillus acidophilus to triple therapy increases eradication

Patient	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
dyspepsia and H. pylori infection  a	triple therapy and Lactobacillus acidophilus	triple therapy alone	H. pylori eradication at weeks	70%	24% (2% to 50%)	6 (3 to 45)