Browse Guides  internal medicine  gastroenterology

Upper gastrointestinal bleed

Prevalence
Causes
Clinical features
Investigations
Therapy
Prevention
Prognosis
Prevention

Varices

In addition give or octreotide (50 micrograms subcutaneously twice daily for 6 months). a

Why?

  • It reduces rebleeding and death. a

Octreotide combined with sclerotherapy helps reduce recurrent bleeding and death

Patient Treatment Comparison Outcome CER RRR
(95% CI)
NNT
(95% CI)
recent first variceal bleed a sclerotherapy and octreotide sclerotherapy recurrent variceal bleed
at 6 months
32% 86%
(-3% to 98%)
3
(2 to 10)
      death
at 6 months
32% 100%
3
(2 to 12)

Expiry date: July 2003
Levels of Evidence used in grading these guides

Author   A   Townsend , CM   Ball
Reviewer   L   Friedman
CAT Writers   A   Townsend , CM   Ball , CJ   Wotton