Evidence-based On-call

internal medicine

gastroenterology

Upper gastrointestinal bleed

Prevalence
Causes
Clinical features
Investigations
Therapy
Prevention
Prognosis

Prevention

Varices

There is no clear benefit from combining beta-blockers and isosorbide mononitrate ^d

Why?

There is no clear reduction in the rate of rebleeding using nadolol and isosorbide mononitrate compared with nadolol alone. ^d

Expiry date: July 2003
Levels of Evidence used in grading these guides

Author	A Townsend , CM Ball
Reviewer	L Friedman
CAT Writers	A Townsend , CM Ball , CJ Wotton