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Upper gastrointestinal bleed

Prevalence
Causes
Clinical features
Investigations
Therapy
Prevention
Prognosis
Causes

Common causes include b c  
  • gastric or duodenal ulcers
  • gastric erosions
  • varices
  • Mallory-Weiss tear
  • oesophagitis
Rarer causes include  
  • tumours b
  • angiodysplasia

Note:

Ulcers, erosions and varices are the commonest causes of upper gastrointestinal haemorrhage

Differential diagnosis b c   %
(95% CI)
duodenal ulcer  24%
(23% to 26%)
gastric erosions  24%
(22% to 25%)
gastric ulcer  21%
(20% to 23%)
varices  10%
(9.0% to 12%)
Mallory-Weiss tear  7.2%
(6.1% to 8.3%)
oesophagitis  6.3%
(5.3% to 7.3%)
erosive duodenitis  5.8%
(4.8% to 6.7%)
neoplasm  2.9%
(2.2% to 3.6%)
stomal ulcer  1.8%
(1.3% to 2.4%)
oesophageal ulcer  1.7%
(1.1% to 2.2%)
Osler-Rendu-Weber telangiectasia  0.49%
(0.20% to 0.79%)
other  6.3%
(5.2% to 7.3%)

 


Expiry date: July 2003
Levels of Evidence used in grading these guides

Author   A   Townsend , CM   Ball
Reviewer   L   Friedman
CAT Writers   A   Townsend , CM   Ball , CJ   Wotton