Therapy

• flecainide ^a

Why?

• Flecainide is more effective at cardioversion than verapamil ^a
• Watch for severe hypotension ^a

Flecainide is more effective at cardioversion than procainamide, digoxin or verapamil

Patient	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
paroxysmal atrial flutter a	flecainide	verapamil	sinus rhythm at 60 minutes	5.0%	1300% (100% to 9600%)	2 (1 to 2)
recent-onset AF a	flecainide	digoxin	severe hypotension at 6 hours	5.9%	-270% (-1100% to -9%)	-6 (-37 to -3)