Therapy

Alternatives include 

• paroxetine  ^a

Why?

• It reduces recurrent episodes in patients resistant or intolerant of other medication ^a

Severe vasovagal syncope: paroxetine reduces recurrent episodes

Patient	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
severe vasovagal syncope a	paroxetine	placebo	recurrent syncope at 2 years	53%	65% (26% to 85%)	3 (2 to 7)