Prognosis

• frequent (> 10/ hour ) or repetitive (> 2 consecutive) premature ventricular contractions ^a
• sinus pause > 2 sec ^a

Heart and renal failure and certain arrhythmias increase the risk of dying

Patient	Prognostic Factor	Outcome	CER	OR (95% CI)	NNF+ (95% CI)
unexplained syncope a	congestive heart failure independent	death at 2 years	16% (11% to 20%)	4 (1.9 to 8.1)	4 (2 to 10)
	creatinine > 2.0 mg/dl independent			7.9 (3.3 to 18.9)	2 (2 to 4)
	frequent or repetitive PVCs independent			3.7 (1.8 to 7.5)	4 (2 to 11)
	sinus pause > 2 sec independent			3.3 (1.1 to 9.6)	4 (2 to 77)

Frequent or repetitive premature ventricular contractions increase the risk of sudden death

Patient	Prognostic Factor	Outcome	CER	OR (95% CI)	NNF+ (95% CI)
unexplained syncope a	frequent or repetitive PVCs independent	sudden death at 2 years	7% (4% to 10%)	14.9 (4 to 55.7)	2 (1 to 6)