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Syncope

Causes
Clinical features
Investigations
Therapy
Prognosis
Investigations

Consider the following if seizures are suspected:
  • EEG c
  • hyperventilation test: (at least 2 symptoms associated with episode reproduced) c

Why?

Epileptiform features on an EEG makes a seizure more likely, and a positive hyperventilation test makes one less likely

Patient Target Disorder and
Reference Standard
Diagnostic Test LR+
(95% CI)
Post-test Probability LR-
(95% CI)
Post-test Probability
unexplained transient loss of consciousness c (pre-test probability: 38%) seizure
(clinical features)
epileptiform EEG 7.4
(2.7 to 21)
82% 0.63
(0.50 to 0.81)
28%
    hyperventilation test 0.29
(0.13 to 0.62)
15% 1.9
(1.4 to 2.8)
54%
 

Expiry date: June 2004
Levels of Evidence used in grading these guides

Author   CM   Ball
Reviewer   W N   Kapoor
CAT Writers   CM   Ball , B   Phillips , CJ   Wotton