Therapy

Why?

• Tinzaparin does not increase functional independence or recurrent stroke compared with aspirin. ^d
• Fewer patients on tinzaparin have a deep vein thrombosis, but more have symptomatic intracranial bleeds. ^a

Tinzaparin reduces deep vein thrombosis but increases intracranial haemorrhage

Patient	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
recent stroke a	tinzaparin for 10 days then aspirin	aspirin	deep vein thrombosis at 15 days	1.9%	83% (38% to 95%)	64 (36 to 340)
			symptomatic intracranial haemorrhage at 15 days	0.21%	-410% (-3800% to 35%)	-120 (-1300 to -62)