Browse Guides  internal medicine  neurology

Stroke

Prevalence
Clinical features
Investigations
Therapy
Prevention
Prognosis
Prognosis

Deterioration

Many patients with stroke will get worse over the next few days b

Why?

A third of patients with a haemorrhage or non-cardioembolic infarction worsen

Type of stroke b % with neurological worsening 
(95% CI)
brain haemorrhage 38% 
(33% to 43%)
cardioembolic infarction 15% 
(13% to 18%)
non-cardioembolic infarction 34% 
(32% to 36%)
  • 41% of patients with acute thromboembolic ischaemic stroke will deteriorate over the first 48 hours (95% CI: 31% to 51%) . a
  • A quarter of patients with an intracranial haemorrhage deteriorate within 24 hours of admission (23%: 95% CI: 15% to 32%). a

 

Stroke subtype can help identify patients at risk of early deterioration

Type of stroke b % deteriorating within 7 days 
(95% CI)
NNF 
(95% CI)
TACI 42%
(31% to 52%)
2
(2 to 3)
PACI 6.3%
(0.2% to 12.4%)
16
(8 to 300)
LACI 26%
(19% to 34%)
4
(3 to 5)
POCI 22%
(11% to 32%)
4
(3 to 9)

 

 

 

Expiry date: October 2003
Levels of Evidence used in grading these guides

Author   CM   Ball
Reviewer   G  Donnan
CAT Writers   CJ   Wotton , N   Shenker , CM   Ball