Browse Guides  internal medicine  neurology

Stroke

Prevalence
Clinical features
Investigations
Therapy
Prevention
Prognosis
Prevention

Acute ischaemic stroke or transient ischaemic attack

Treat hypertension a

Why?

  • It reduces recurrent strokes, fatal strokes and major cardiovascular events, though there is no clear reduction in mortality. a

Treating hypertension reduces further strokes and major cardiovascular events

Patient Treatment Comparison Outcome CER RRR
(95% CI)
NNT
(95% CI)
previous stroke or TIA a blood pressure lowering medication placebo stroke
at years
9.5% 26%
(14% to 37%)
40
(26 to 84)
      fatal stroke
at years
3.3% 28%
(5% to 46%)
110
(58 to 700)
      major cardiovascular events
at years
11% 20%
(7% to 30%)
45
(27 to 130)

Expiry date: October 2003
Levels of Evidence used in grading these guides

Author   CM   Ball
Reviewer   G  Donnan
CAT Writers   CJ   Wotton , N   Shenker , CM   Ball