Prevention

Consider adding dipyridamole ^a

Why?

• Aspirin and dipyridamole reduces recurrent stroke more effectively than aspirin, but increases the risk of moderate or severe bleeding. There is no clear effect on mortality. ^a

Dipyridamole added to aspirin reduces stroke better than aspirin alone, but causes more bleeding

Patient	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
recent TIA or ischaemic stroke a	aspirin and dipyridamole	aspirin	stroke at 2 years	13%	29% (14% to 42%)	25 (16 to 57)
			moderate or severe bleed at 2 years		-140% (-280% to -48%)	-48 (-99 to -31)