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Stroke

Prevalence
Clinical features
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Therapy
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Prognosis
Prevention

Carotid endarterectomy

Surgical complications are more likely with associated stroke risk factors:  

  • atrial fibrillation b
  • congestive heart failure b
  • hypertension b
  • a recent stroke or TIA b particularly if more severe b

Why?

Stroke risk factors increase the risk of surgical complications

Patient Prognostic Factor Outcome CER OR
(95% CI)
NNF+
(95% CI)
undergoing carotid endarterectomy b hypertension
independent
stroke or death
at 30 days
8.6% 1.82
(1.37 to 2.41)
17
(10 to 36)
undergoing carotid endarterectomy b history of congestive heart failure
independent
stroke or death
at 30 days
8.6% 2.60
(1.20 to 5.60)
9
(4 to 65)
carotid endarterectomy b atrial fibrillation
independent
death
at uncertain duration
1.2% 2.02 84
undergoing carotid endarterectomy b monocular vs cerebral transient ischaemic attack
independent
stroke or death
at 30 days
8.6% 0.49
(0.37 to 0.66)
-24
(-36 to -19)

A more severe stroke increases the risk of surgical complications

Patient Prognostic Factor Outcome CER RR
(95% CI)
NNF+
(95% CI)
undergoing carotid endarterectomy b evolving stroke
independent
death, stroke, myocardial infarction
at 30 days
11% 7.58
(1.54 to 15.0)
1
(1 to 17)
  recent stroke
independent
    2.42
(1.10 to 4.84)
6
(2 to 91)
  carotid transient ischaemic attack
independent
    1.74
(1.06 to 2.79)
12
(5 to 150)

Expiry date: October 2003
Levels of Evidence used in grading these guides

Author   CM   Ball
Reviewer   G  Donnan
CAT Writers   CJ   Wotton , N   Shenker , CM   Ball