Prevention

Give patients low-dose aspirin ^a

Why?

• It leads to fewer strokes and myocardial infarctions than high-dose aspirin ^a

Carotid endarterectomy: low-dose aspirin prevents more strokes and myocardial infarctions than high-dose

Patient	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
undergoing carotid endarterectomy a	aspirin 81 or 325 mg daily	aspirin 650 mg or 1300 mg daily	stroke	6.7%	32% (7% to 50%)	46 (26 to 220)
			myocardial infarction	2.5%	1.3% (0.35% to 2.3%)	75 (43 to 290)