Evidence-based On-call

Stroke

Clinical features

Listen for mitral valve prolapse ^b

Why?

2% of patients with mitral valve prolapse aged > 35 will have a stroke within 10 years (2.0%: 95% CI: 1.2% to 2.9%) ^b

Mitral valve prolapse: ischaemic heart disease and diabetes mellitus increase the risk of stroke

Patient	Prognostic Factor	Outcome	CER	OR (95% CI)	NNF+ (95% CI)
mitral valve prolapse ^b	ischaemic heart disease independent	stroke at 10 years	2%	3.30 (1.30 to 8.60)	23 (8 to 170)
	diabetes independent			4.60 (1.20 to 17.2)	15 (4 to 250)