Therapy

•  try phenobarbital ^a 15 mg/kg iv at 100 mg/min
  

Why?

• It terminates more seizures than diazepam and phenytoin
• It works faster than diazepam and phenytoin (on average 4 minutes faster) ^a
• The effect on subsequent intubations or need for a general anaesthetic is unclear.

Phenobarbital with optional phenytoin terminates more seizures than diazepam and phenytoin

Patient	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
status epilepticus a	phenobarbital with optional phenytoin	diazepam and phenytoin	termination of seizures at 10 minutes	55%	75% (-2% to 94%)	3 (2 to 16)