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Status epilepticus

Prevalence
Causes
Clinical features
Investigations
Therapy
Prognosis
Therapy

Get help. d

Check airway, breathing, circulation. a

Give 

  • oxygen b  
  • lorazepam a  0.1 mg/kg iv at 2 mg/min
  • or diazepam a  0.15 mg/kg iv at 5 mg/min
    An alternative route is rectally; using larger doses a  
 

Fits often continue. b  If they do, try

  • phenobarbital a 15 mg/kg iv at 100 mg/min
then
  • phenytoin c  18 mg/kg iv at 50 mg/min
If fits continue (especially if > 1 hour), b intubate and anaesthetise with either
  • propofol c  
  • midazolam d 
  • thiopental d
Watch for side-effects of medication - they are common, so monitor patients continuously. a  

On recovery, fully conscious patients not on medication can be rapidly loaded with oral phenytoin (try 18 mg/kg). c  


Expiry date: September 2004
Levels of Evidence used in grading these guides

Author   RS   Phillips, CM   Ball
Reviewer   S   Straus
CAT Writer   RS   Phillips, C   Wotton, CM   Ball