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Sickle cell crisis

Prevalence
Clinical features
Investigations
Therapy
Prevention
Prognosis
Prevention

Give stilbestrol 5 mg orally daily to patients with frequent attacks a

Why?

Stilboestrol stops stuttering priapism in patients with more than 2 attacks a week

Patient Treatment Comparison Outcome CER RRR
(95% CI)
NNT
(95% CI)
stuttering priapism with > 2 attacks per week a stilboestrol placebo continuing attacks
at 2 weeks
80% 100%
1
(1 to 2)

 

Expiry date: May 2004
Levels of Evidence used in grading these guides

Author    CM  Ball, RS Phillips
Reviewer   G   Serjeant
CAT Writer     CM  Ball, N  Shenker