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Sickle cell crisis

Prevalence
Clinical features
Investigations
Therapy
Prevention
Prognosis
Prevalence

Most patients requiring admission present with painful vaso-occlusive crises c .  The type of presentation varies with the age of patient. c

Note:

Most patients present with a painful vaso-occlusive crisis

type of presentation %
(95% CI)
vaso-occlusive c 91%
(87% to 96%)
  • painful c
88%
(83% to 93%)
  • stroke (in children) c
1.9%
(0.0% to 4.0%)
  • renal papillary necrosis c
1.9%
(0.0% to 4.0%)
syndromes c 16%
(9.9% to 21%)
  • girdle (in adolescence)
8.1%
(3.9% to 12%)
  • acute chest syndrome
6.2%
(2.5% to 9.9%)
  • hepatic
0.6%
(0.0% to 1.8%)
  • splenic
0.6%
(0.0% to 1.8%)
infective c 7%

  

 

Expiry date: May 2004
Levels of Evidence used in grading these guides

Author    CM  Ball, RS Phillips
Reviewer   G   Serjeant
CAT Writer     CM  Ball, N  Shenker