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Pulmonary embolism

Prevalence
Clinical features
Differential Diagnosis
Investigations
Therapy
Prevention
Prognosis
Prognosis

A poor prognosis is associated with  
  • cancer a
  • chronic lung disease a
  • left heart failure a
  • immobility a
  • surgery within the last 3 months a
  • a history of thrombophlebitis a

Why?

Cancer, heart failure and chronic lung disease increase the risk of dying following a PE

Patient Prognostic Factor Outcome CER RR
(95% CI)
NNF+
(95% CI)
pulmonary embolism a cancer
independent
death
at 12 months
18% 4.4
(2.1 to 9.5)
2
(1 to 5)
  left heart failure
independent
  18% 2.6
(1.2 to 5.7)
3
(1 to 27)
  chronic lung disease
independent
  19% 3.2
(1.3 to 7.4)
2
(1 to 17)
pulmonary embolism a immobilisation
not independent
death
at 12 months
15% 1.76
(1.43 to 2.15)
9
(6 to 16)
  surgery within 3 months
not independent
  15% 1.69
(1.38 to 2.07)
10
(6 to 18)
  history of thrombophlebitis
not independent
  15% 1.34
(1.03 to 1.81)
20
(8 to 220)

 

Expiry date: July 2003
Levels of Evidence used in grading these guides

Author   CM   Ball
Reviewer   B   Lee
CAT Writers   CM   Ball, C Wotton, M Hayatli