Therapy

Why?

• Adding enoxaparin compared with heparin to tenecteplase reduces reinfarction and refractory ischaemia in hospital. ^a  
• There is no clear increase in death, major haemorrhage or thrombocytopenia. ^a  

Adding enoxaparin to tenecteplase leads to less reinfarction and refractory ischaemia than adding heparin

Patient	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
myocardial infarction a	tenecteplase and enoxaparin	tenecteplase and unfractionated heparin	inhospital reinfarction at 30 days	4.2%	37% (12% to 55%)	64 (37 to 220)
			inhospital refractory ischaemia at 30 days	6.5%	30% (9% to 46%)	52 (30 to 190)