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Myocardial infarction

Prevalence
Clinical features
Differential diagnosis
Investigations
Therapy
Prevention
Prognosis
Prognosis

Death

The risk of dying is increased with arrhythmias 

  • 10 or more premature ventricular contractions per hour  a b
  • ventricular fibrillation (particularly after 48 hours) a   b
  • 2nd b or 3rd degree heart block a b after 24 hours
  • cardiac arrest a b

Why?

Ventricular arrhythmias and heart block increase the risk of dying

Patient Prognostic Factor Outcome CER OR
(95% CI)
NNF+
(95% CI)
myocardial infarction a 10 or more premature ventricular contractions per hour
independent
death
at 18 months
5.8% 6.06
(1.90 to 19.4)
5
(2 to 21)
myocardial infarction b complex ventricular arrhythmias
independent
death
at 6 months
3.0% 2.55
(1.96 to 3.32)
23
(16 to 37)
first myocardial infarction b VF within 4 hours of infarction
independent
death
at uncertain duration
4.0% 2.47
(1.48 to 4.13)
19
(9 to 55)
first myocardial infarction VF >4hrs but <48hrs after infarction
independent
death
at uncertain duration
4.0% 3.97
(1.51 to 10.5)
10
(4 to 52)
first myocardial infarction VF >48hrs after infarction
independent
death
at uncertain duration
4.0% 20.2
(11.5 to 35.5)
2
(2 to 4)
myocardial infarction b 2nd or 3rd degree heart block
independent
death
at uncertain duration
4.0% 2.89
(2.03 to 4.09)
15
(9 to 26)
inferior MI a complete heart block
independent
death
at 12 months
16% 2.7
(1.3 to 5.5)
5
(3 to 25)
 

Expiry date: November 2003
Levels of Evidence used in grading these guides

Author   CM   Ball , N   Shenker
Reviewer   S   Straus
CAT Writers   CJ   Wotton , N   Shenker , B   Phillips , CM   Ball