Prevention

using gemfibrozil for patients with a low HDL levels ^a

Why?

• Men with low HDL levels who take gemfibrozil are less likely to have a myocardial infarction or die from heart disease. There is no clear effect on stroke. ^a

Gemfibrozil reduces MI and death from heart disease in patients with low HDL levels

Patient	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
MI or angina, and HDL < 1.0 mmol/l a	gemfibrozil	placebo	nonfatal myocardial infarction or death due to heart disease at 5 years	22%	20% (6.0% to 32%)	23 (12 to 77)