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Myocardial infarction

Prevalence
Clinical features
Differential diagnosis
Investigations
Therapy
Prevention
Prognosis
Prevention

Refer all patients for arteriography (followed by PTCA or CABG as required) if they develop a
  • symptomatic angina pectoris during predischarge exercise test
  • ST changes during exercise, compatible with ischaemia
Why?
  • Performing angiography followed by PTCA or CABG on all patients with post-infarction ischaemia reduces subsequent reinfarction and unstable angina compared with conservative management unless patients have severe angina.  There is no clear effect on mortality. a

Invasive therapy following MI reduces reinfarction and unstable angina compared with conservative therapy

Patient Treatment Comparison Outcome CER RRR
(95% CI)
NNT (95% CI)
myocardial infarction a invasive therapy (arteriography and PTCA or CABG) medical therapy unstable angina
at 12 months
39% 39%
(24% to 52%)
9
(6 to 16)
      reinfarction at 12 months 11% 47% (18% to 66%) 20  (12 to 63)

 

Expiry date: November 2003
Levels of Evidence used in grading these guides

Author   CM   Ball , N   Shenker
Reviewer   S   Straus
CAT Writers   CJ   Wotton , N   Shenker , B   Phillips , CM   Ball