Browse Guides  internal medicine  cardiology

Myocardial infarction

Prevalence
Clinical features
Differential diagnosis
Investigations
Therapy
Prevention
Prognosis
Prevention

Perform stress-testing using any of 
  • myocardial perfusion imaging b
  • echocardiography b
  • symptom-limited c exercise tolerance test looking for b
    • limited exercise duration
    • impaired systolic blood pressure changes
    • impaired systolic blood pressure changes

Why?

  • Patients who have symptom-limited tolerance tests compared with low-level tests are more likely to show signs of ischaemia. c
  • Abnormal exercise tolerance tests slightly increase the risk of dying from heart disease. b
  • ST-segment depression on exercise test increases the risk of recurrent myocardial infarction. a

Abnormal tress testing slightly increases the risk of dying from heart disease

Patient Prognostic Factor Outcome CER OR
(95% CI)
NNF+
(95% CI)
myocardial infarction b exercise ECG: ST depression >1mm
independent
death from heart disease
at months
4.4% 1.7
(1.2 to 2.5)
35
(17 to 120)
  exercise ECG: impaired systolic BP
independent
    4.0
(2.5 to 6.3)
9
(6 to 17)
  exercise ECG: limited exercise duration
independent
    4.0
(1.9 to 8.4)
9
(4 to 27)
  myocardial perfusion imaging; exercise testing: reversible perfusion defect
independent
    3.1
(1.6 to 4.6)
12
(8 to 41)
  Ventricular function; exercise stress: ejection fraction < 40%
independent
    3.2 12
  Ventricular function; exercise stress: ejection fraction change <5%
independent
    4.2 8
  Ventricular function; exercise stress: new dyssynergy
independent
    1.2 120
  Ventricular function; pharmacological stress: new dyssynergy
independent
    2.7
(1.4 to 5.2)
15
(7 to 60)

 

Expiry date: November 2003
Levels of Evidence used in grading these guides

Author   CM   Ball , N   Shenker
Reviewer   S   Straus
CAT Writers   CJ   Wotton , N   Shenker , B   Phillips , CM   Ball