Prevention

Why?

• Patients with an acute MI or congestive heart failure who take prophylactic amiodarone are less likely to die particularly from arrhythmias. ^a

Amiodarone reduces death

Patient	Treatment	Comparison	Outcome	CER	OR (95% CI)	NNT (95% CI)
acute MI or congestive heart failure a	amiodarone	placebo or usual care	death at months	8.6%	0.87 (0.78 to 0.99)	97 (57 to 1300)
			arrhythmic or sudden death at months	4.0%	0.71 (0.59 to 0.85)	90 (63 to 180)