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Meningitis

Prevalence
Causes
Clinical features
Differential Diagnosis
Investigations
Therapy
Prevention
Prognosis
Prognosis

A clinical prediction rule can help identify patients with meningococcal disease at risk of dying. a  

Look for the following prognostic factors, and sum the score.

Prognostic factors a Score
frank bleeding 2
focal neurological signs 1
aged 60 or more 1
preadmission antibiotics -1


Why?

A clinical prediction rule can help identify patients with meningococcal disease at risk of dying. a 

Patient Outcome %
(95% CI)
NNF
(95% CI)
proven meningococcal disease a death
at 7 days
6.0%
(3.2% to 8.8%)
17
(11 to 31)
score 2 or more death
at 7 days
80%
(55% to 100%)
1
(1 to 2)
score 1 death
at 7 days
30%
(9.9% to 50%)
3
(2 to 10)
score 0 death
at 7 days
1.9%
(0.0% to 4.0%)
53
(25 to infinity)
score -1 death
at 7 days
0.0%
(0.0% to 1.1%)
-
(91 to infinity)

Expiry date: January 2003
Levels of Evidence used in grading these guides

Authors   RS   Phillips , C   Ball
Reviewer   B   Davis
CAT Writers   C   Ball , RS   Phillips , C   Wotton