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Meningitis

Prevalence
Causes
Clinical features
Differential Diagnosis
Investigations
Therapy
Prevention
Prognosis
Investigations
  • blood countd
  • clotting studiesd
  • urea, electrolytes, creatinined
  • glucosed
  • blood culturesa
  • chest X-rayd
  • throat swabd
  • lumbar puncture a
    • Considering arranging a CT brain before performing the lumbar puncture a .
    • Use a narrow gauge, non-cutting needle a through a bleb of local anaesthetic c
    • Replace the stylet before withdrawing the needle. a
    • Consider using an epidural blood patch. a
    • There is no clear benefit from
      • bedrest post-lumbar puncture.
      • fluid supplementation d

    Send CSF for 
    • Gram stain and cell count c
    • culture
    • glucose and protein c

    Consider 
    • using reagent strips (e.g. urine dipsticks) a b to look for leucocyte esterase, glucose and protein levels
    • blood for PCR for meningococcus b
    • CSF for PCR for meningococcus b or viruses c
    • Latex agglutination tests for diagnosing meningococcal, pneumococcal or H. influenzae b infections c

Expiry date: January 2003
Levels of Evidence used in grading these guides

Authors   RS   Phillips , C   Ball
Reviewer   B   Davis
CAT Writers   C   Ball , RS   Phillips , C   Wotton