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Meningitis

Prevalence
Causes
Clinical features
Differential Diagnosis
Investigations
Therapy
Prevention
Prognosis
Clinical features

Look for Kernig's sign b

Positive if the patient's headache worsens on flexing the patient's legs at the hip and extending them at the knees.

Why?

An absent Kernig's sign does not rule out meningitis

Patient Target Disorder and
Reference Standard
Diagnostic Test LR+
(95% CI)
Post-test Probability LR-
(95% CI)
Post-test Probability
recent-onset headache and fever b (pre-test probability: 63%) CSF pleocytosis
( 5 or more white cells per mm 3 of CSF )
positive Kernig's sign -
(0.62 to infinity)
100% 0.91
(0.82 to 1.0)
61%

Expiry date: January 2003
Levels of Evidence used in grading these guides

Authors   RS   Phillips , C   Ball
Reviewer   B   Davis
CAT Writers   C   Ball , RS   Phillips , C   Wotton