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Meningitis

Prevalence
Causes
Clinical features
Differential Diagnosis
Investigations
Therapy
Prevention
Prognosis
Clinical features

Look for neck stiffness b

Why?

Lack of neck stiffness does not rule out meningitis

Patient Target Disorder and
Reference Standard
Diagnostic Test LR+
(95% CI)
Post-test Probability LR-
(95% CI)
Post-test Probability
recent-onset headache and fever b (pre-test probability: %) CSF pleocytosis
( 5 or more white cells per mm 3 of CSF )
neck stiffness -
(1.1 to infinity)
100% 0.85
(0.75 to 0.98)
59%
  • Neck stiffness is common in elderly patients without meningitis (35%). b

Expiry date: January 2003
Levels of Evidence used in grading these guides

Authors   RS   Phillips , C   Ball
Reviewer   B   Davis
CAT Writers   C   Ball , RS   Phillips , C   Wotton