Therapy

• iv hydrocortisone 200 mg iv three times a day
• prednisolone 30 mg daily by mouth
• prednisone 30 mg daily by mouth

• Steroids increase the rate of remission in active ulcerative colitis ^a or Crohn's disease ^a

Steroids induce remission in active inflammatory bowel disease

Patient	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
active ulcerative colitis a	oral prednisone	placebo	remission at 28 days	17%	310% (40% to 1100%)	2 (1 to 4)
active Crohn's disease a	oral prednisone	placebo	remission at 17 weeks	26%	100% (33% to 210%)	4 (2 to 8)