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Inflammatory bowel disease

Prevalence
Clinical features
Differential Diagnosis
Investigations
Therapy
Prevention
Prognosis
Prognosis

Systemic manifestations are uncommon. b

Note:

The commonest systemic manifestations of ulcerative colitis are joint disease and kidney stones

Systemic manifestationb Ulcerative colitis % 
(95% CI)
joints 8.5% 
(6.9% to 10%)
skin 3.4% 
(2.3% to 4.5%)
liver 1.3% 
(0.7% to 2.0%)
retarded growth 1.3% 
(0.7% to 2.0%)
urolithiasis 6.5% 
(5.0% to 7.9%)
cholelithiasis 4.1% 
(3.0% to 5.3%)
  • Many patients have multiple manifestations. c
  • No manifestation is clearly commoner in Crohn's disease than ulcerative colitis, except for malabsorption. (10% of patients with Crohn's disease in one study) c


Expiry date: July 2003
Levels of Evidence used in grading these guides

Author   CM   Ball
Reviewer   L   Friedman
CAT Writers   D   Ford , CM   Ball