Prognosis

• toxic, fulminant or severe colitis 
• joint symptoms 
• left-sided disease at diagnosis 

Note:

• 61% of patients with ulcerative colitis have disease extension (95% CI: 58% to 64%) ^b  

Ulcerative colitis severe colitis, left-sided disease and joint symptoms increase the risk of disease extension

Patient	Prognostic Factor	Outcome	CER	OR (95% CI)	NNF+ (95% CI)
ulcerative colitis b	toxic, fulminant or severe colitis not independent	disease extension at 13 years	61% (58% to 64%)	14.8 (3.5 to 63.1)	2 (2 to 4)
	left-sided disease extent at diagnosis independent	disease extension at 13 years		2.5 (1.6 to 3.9)	5 (4 to 9)
	joint symptoms independent	disease extension at 13 years		3.7 (1.6 to 8.6)	4 (3 to 9)