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Inflammatory bowel disease

Prevalence
Clinical features
Differential Diagnosis
Investigations
Therapy
Prevention
Prognosis
Prognosis

Relapse and subsequent surgery are common following discharge  b but death is uncommon. b

Why?

Most patients relapse and many require surgery

Outcome %
(95% CI)
Crohn's disease relapse at 10 years b 99%
(97% to 100%)
Crohn's disease surgery at 6 years b 55%
(48% to 62%)
definite ulcerative colitis relapse at 7 years b 75%
(70% to 80%)
indeterminate colitis relapse at 7 years b 83%
(74% to 91%)
ulcerative colitis: surgery at 13 years b 38%
(35% to 41%)
ulcerative colitis: toxic, fulminant or severe colitis at 13 years b 13%
(11% to 15%)
ulcerative colitis: bleeding at 13 years b 17%
(15% to 19%)
ulcerative colitis: death at 13 years b 1.0%
(0.4% to 1.6%)

Expiry date: July 2003
Levels of Evidence used in grading these guides

Author   CM   Ball
Reviewer   L   Friedman
CAT Writers   D   Ford , CM   Ball