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Inflammatory bowel disease

Prevalence
Clinical features
Differential Diagnosis
Investigations
Therapy
Prevention
Prognosis
Investigations
  • blood count c
  • ESR c

Why?

An elevated platelet count can help diagnose inflammatory bowel disease

Patient Target Disorder and
Reference Standard
Diagnostic Test LR+
(95% CI)
Post-test Probability LR-
(95% CI)
Post-test Probability
inflammatory bowel disease c   (pre-test probability: 11%) inflammatory bowel disease
  (endoscopy or histology)
anaemia (Hb < 12 g/dl in women, < 14 g/dl in men) 2.7
(1.8 to 4.0)
25% 0.52
(0.33 to 0.83)
6%
    white cell count > 10 x 109/l 2.2
(1.5 to 3.3)
22% 0.59
(0.39 to 0.91)
7%
    platelet count > 450 x 109/l 42
(13 to 130)
84% 0.41
(0.26 to 0.65)
5%
    ESR > 30 mm/h 1.9
(1.3 to 2.6)
21% 0.71
(0.50 to 0.995)
8%

Expiry date: July 2003
Levels of Evidence used in grading these guides

Author   CM   Ball
Reviewer   L   Friedman
CAT Writers   D   Ford , CM   Ball