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Inflammatory bowel disease

Prevalence
Clinical features
Differential Diagnosis
Investigations
Therapy
Prevention
Prognosis
Clinical features

First attack of colitis

Ask about

  • speed of onset c  
  • any diarrhoea a
    • its duration c
    • the number of bowel movements per day at onset c  
  • any fever c  
  • any recent travel abroad c  
  • any weight loss a 
  • a family history of inflammatory bowel disease a 
Look for c  
  • macroscopically bloody stool
  • severe abdominal pain
  • vomiting   
  • dehydration or hypovolaemia d
  • evidence of septicaemia or septic shock d
  • evidence of perforation d

Known Crohn's disease

Ask patients about c  
  • their general well-being in the last 24 hours
  • any abdominal pain in the last 24 hours
  • the number of liquid stools per day
and look for c  
  • an abdominal mass
  • any systemic complications 
    • arthralgia
    • uveitis
    • erythema nodosum, pyoderma gangrenosum
    • aphthous ulcers
    • anal fissure
    • new fistula
    • abscess
Watch out for c  
  • weight loss > 2.5 kg
  • lower gastrointestinal bleeding
  • anal fissures or abscesses   
  • dehydration or hypovolaemia d
  • evidence of septicaemia or septic shock d
  • evidence of perforation d

Known ulcerative colitis

Ask patients about
  • number of bowel motions per day, and whether there was any blood c
Look for c  
  • tachycardia
  • evidence of septicaemia or septic shock d
    • fever
    • raised ESR
  • anaemia
  • dehydration or hypovolaemia d
  • evidence of perforation d
Remember
  • Deep ulceration is common, but clinical features cannot predict which patients have it. c Further investigations are required. b

Expiry date: July 2003
Levels of Evidence used in grading these guides

Author   CM   Ball
Reviewer   L   Friedman
CAT Writers   D   Ford , CM   Ball