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Infective endocarditis

Prevalence
Clinical features
Investigations
Therapy
Prevention
Prognosis
Prevention

 Use antibiotic prophylaxis for high-risk patients (valvular heart disease, prosthetic heart valves, previous rheumatic fever or infective endocarditis) during dental surgery a and invasive procedures c  

Why?

  • Antibiotic prophylaxis to prevent infective endocarditis in high risk patients undergoing dental extraction saves money. a
  • Antibiotic prophylaxis following an invasive procedure reduces the risk of infective endocarditis in patients with prosthetic heart valves. c

Antibiotic prophylaxis for patients at risk of infective endocarditis reduces it

Patient Treatment Comparison Outcome CER RRR
(95% CI)		 NNT
(95% CI)
prosthetic heart valve c oral antibiotic prophylaxis no antibiotics infective endocarditis
at 2 weeks 		2.0% 100%
 51
(28 to 240)

 

Expiry date: July 2003
Levels of Evidence used in grading these guides

Authors   CM   Ball , C   Hennigan , S   Dhingra
Reviewer   E   Abrutyn
CAT Writers   CM   Ball , C   Hennigan , S   Dhingra