Investigations

• ECG ^b

Why?

Conduction abnormalities on ECG make perivalvular abscesses more likely

Patient b	Target Disorder and Reference Standard	Diagnostic Test	LR+ (95% CI)	Post-test Probability	LR- (95% CI)	Post-test Probability
suspected infective endocarditis (pre-test probability: 56%)	perivalvular abscesses (pathological evidence)	atrioventricular and/ or bundle branch or fascicular blocks on ECG	4.5 (1.2 to 17)	86%	0.61 (0.45 to 0.84)	44%