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Hyponatraemia

Prevalence
Causes
Clinical features
Investigations
Therapy
Prognosis
Clinical features

Look for evidence of oedema or dehydration c

When assessing for dehydration, look for a

  • sunken eyes
  • dry axillae
  • dry nose or mouth mucous membranes
  • longitudinal furrows on the tongue

Why?

Sunken eyes, dry axillae, dry mucous membranes and tongue furrows make dehydration more likely

    Patient a Target Disorder and
    Reference Standard
    Diagnostic Test LR+
    (95% CI)
    Post-test Probability LR-
    (95% CI)
    Post-test Probability
    suspected hypovolaemia ot due to blood loss
    (pre-test probability: 15%)
    hypovolaemia not due to blood loss
    (biochemistry)
    sunken eyes 3.4
    (1.0 to 12)
    38% 0.5
    (0.3 to 0.7)
    8%
        dry axillae 2.8
    (1.4 to 5.4)
    33% 0.6
    (0.4 to 1.0)
    10%
        dry mouth and mucous membranes 2.0
    (1.0 to 4.0)
    26% 0.3
    (0.1 to 0.6)
    5%
        longitudinal furrows on tongue 2.0
    (1.0 to 4.0)
    26% 0.3
    (0.1 to 0.6)
    5

Note:

  • The following are not very helpful at diagnosing dehydration b
    • postural changes in pulse or blood pressure
    • neurological signs or symptoms (including confusion and slurred speech)

Expiry date: September 2005
Levels of Evidence used in grading these guides

Authors   T   Ringrose , CM   Ball
Reviewer   J V   Bonventre
CAT Writers   T   Ringrose , CM   Ball