Clinical features

Why?

• Patients on an intensive insulin regimen are at increased risk of developing severe hypoglycaemia. ^a

An intensive insulin regimen increases the risk of severe hypoglycaemia

Patient	Treatment	Comparison	Outcome	CER	OR (95% CI)	NNT (95% CI)
type 1 diabetes a	intensive insulin regimen	conventional therapy	severe hypoglycaemia at 2-6 years	30%	2.88 (2.38 to 3.48)	4 (3 to 5)

Note:

• Using human insulin compared with porcine insulin does not increase risk of developing hypoglycaemia. ^b