Therapy

Give steroids to patients with steroid-responsive malignancy 
e.g. breast cancer, myeloma, renal cell carcinoma ^a

Why?

• Women with breast cancer and hypercalcaemia who take prednisolone are more likely to become normocalcaemic. ^a

Prednisolone helps achieve normocalcaemia in women with breast cancer

Patient	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
breast cancer and hypercalcaemia a	prednisolone, furosemide and rehydration	furosemide and rehydration	normocalcaemia at 8 days	0%	47% (14% to 67%)	2 (1 to 5)