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Giant cell arteritis

Prevalence
Clinical features
Differential Diagnosis
Investigations
Therapy
Prognosis
Investigations
  • ESR or plasma viscosity
  • blood count
  • bilateral c temporal artery biopsy  a in areas of pain or inflammation (this increases the chance of a positive biopsy) c
Patients with negative biopsies who meet all the following criteria should be diagnosed with giant cell arteritis. d
  1. aged > 55
  2. a positive response to steroids within 48 hours
  3. a history lasting > 2 weeks
  4. at least 3 of the following
  • proximal and symmetrical girdle or upper arm muscles pain, stiffness, or tenderness
  • jaw claudication
  • clinically abnormal temporal artery (tender, thickened, red)
  • systemic symptoms or signs (malaise, anorexia, weight loss, anaemia, pyrexia)
  • recent onset headache
  • visual disturbance (loss, dip, blurring)

 

Expiry date: January 2004
Levels of Evidence used in grading these guides

Author   CM   Ball
Reviewer   M V   Kyle
CAT Writer   CM   Ball