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Giant cell arteritis

Prevalence
Clinical features
Differential Diagnosis
Investigations
Therapy
Prognosis
Clinical features

Ask about   
  • recent onset headache b
  • jaw claudication b
  • tongue claudication  c
  • anorexia c
  • visual disturbances d

Why?

A recent headache or jaw claudication make giant cell arteritis more likely

Patient Target Disorder and
Reference Standard
Diagnostic Test LR+
(95% CI)
Post-test Probability LR-
(95% CI)
Post-test Probability
suspected giant cell arteritis having a temporal artery biopsy b
(pre-test probability: 53%)
giant cell arteritis
(positive temporal artery biopsy)
recent onset headache 1.7
(1.3 to 2.3)
57% 0.37
(0.20 to 0.70)
23%
suspected giant cell arteritis having a temporal artery biopsy b
(pre-test probability: 53%)
giant cell arteritis
(positive temporal artery biopsy)
jaw claudication 3.5
(1.6 to 7.6)
73% 0.66
(0.50 to 0.86)
34%
suspected giant cell arteritis having a temporal artery biopsy c
(pre-test probability: 40%)
giant cell arteritis
(clinical features or temporal artery biopsy)
tongue claudication 0.11
(0.027 to 0.44)
7% 1.5
(1.2 to 1.7)
50%
suspected giant cell arteritis having a temporal artery biopsy c
(pre-test probability: 36%)
giant cell arteritis
(positive temporal artery biopsy)
anorexia 3.8
(1.4 to 10)
69% 0.77
(0.63 to 0.95)
31%

 

Expiry date: January 2004
Levels of Evidence used in grading these guides

Author   CM   Ball
Reviewer   M V   Kyle
CAT Writer   CM   Ball