Investigations

• scintigraphy ^{a b} - look for a reversible perfusion defect ^b

Scintigraphy makes multivessel coronary artery disease more likely

Patient	Target Disorder and Reference Standard	Diagnostic Test	LR+ (95% CI)	Post-test Probability	LR- (95% CI)	Post-test Probability
chest pain referred for further investigation (pre-test probability: 52%) a	multivessel coronary artery disease (coronary angiography)	scintigraphy	2.5 (1.5 to 4.2)	76%	0.44 (0.29 to 0.67)	36%

Scintigraphy : a reversible perfusion defect makes coronary artery disease more likely

Patient b	Target Disorder and Reference Standard	Diagnostic Test	LR+ (95% CI)	Post-test Probability
suspected coronary artery disease (pre-test probability: 51%)	coronary artery stenosis (coronary angiography)	scintigraphy: reversible perfusion defect	12	93%
		fixed perfusion defect	1.4	59%
		no perfusion defect	0.18	16%